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Descriptor English: NADPH Oxidase 4
Descriptor Spanish: NADPH Oxidasa 4
Descriptor NADPH oxidasa 4
Entry term(s) NAD(P)H oxidasa Renox
NAD(P)H oxidasa renal
oxidasa NAD(P)H renox
proteína NOX4
Scope note: Oxidasa NADPH que se expresa ampliamente en el riñón. Forma un complejo con la CYBA-P22PHOX y produce SUPERÓXIDOS intracelulares que regulan la señalización celular en la APOPTOSIS, RESORCIÓN ÓSEA y activación del FN-KAPPA B.
Descriptor Portuguese: NADPH Oxidase 4
Descriptor French: NADPH Oxidase 4
Entry term(s): Nox4 Protein
Oxidase 4, NADPH
Renal NAD(P)H Oxidase
Renox NAD(P)H Oxidase
Tree number(s): D08.811.682.608.575.937
D12.776.331.894.937
D12.776.543.653.937
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074663
Scope note: An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.6.3.-
Previous Indexing: NADPH Oxidases (2001-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57025
Unique ID: D000074663
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
NADPH Oxidase 4 - Preferred
Concept UI M000627312
Scope note An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
Preferred term NADPH Oxidase 4
Entry term(s) Nox4 Protein
Oxidase 4, NADPH
Renal NAD(P)H Oxidase
Renox NAD(P)H Oxidase



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