| Descriptor English: | Solute Carrier Organic Anion Transporter Family Member 1B3 | ||||||
| Descriptor Spanish: |
Miembro 1B3 de la Familia de los Transportadores de Solutos de Aniones Orgánicos
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| Descriptor Portuguese: | Membro 1B3 da Família de Transportadores de Ânion Orgânico Carreador de Soluto | ||||||
| Descriptor French: | Membre 1B3 de la famille des transporteurs d'anions organiques appartenant aux transporteurs de solutés | ||||||
| Entry term(s): |
Liver Specific Organic Anion Transporter 2 Liver-Specific Organic Anion Transporter-2 OATP1B3 Protein OATP8 Protein SLC21A8 Protein SLCO1B3 Protein Solute Carrier Family 21 Member 8 Protein |
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| Tree number(s): |
D12.776.157.530.450.074.500.781.875 D12.776.157.530.937.905 D12.776.543.585.450.074.500.875.875 D12.776.543.585.937.950 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074542 | ||||||
| Scope note: | A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Organic Anion Transporters, Sodium-Independent (2002-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57083 | ||||||
| Unique ID: | D000074542 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/04/06 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Solute Carrier Organic Anion Transporter Family Member 1B3
- Preferred
| Concept UI |
M000626958 |
| Scope note | A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA. |
| Preferred term | Solute Carrier Organic Anion Transporter Family Member 1B3 |
| Entry term(s) |
Liver Specific Organic Anion Transporter 2 Liver-Specific Organic Anion Transporter-2 OATP1B3 Protein OATP8 Protein SLC21A8 Protein SLCO1B3 Protein Solute Carrier Family 21 Member 8 Protein |
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