| Descriptor English: | Zinc Transporter 8 | ||||||
| Descriptor Spanish: |
Transportador 8 de Zinc
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| Descriptor Portuguese: | Transportador 8 de Zinco | ||||||
| Descriptor French: | Transporteur de zinc ZnT-8 | ||||||
| Entry term(s): |
Slc30A8 Protein Solute Carrier Family 30 Member 8 Protein ZnT 8 Protein ZnT-8 Protein |
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| Tree number(s): |
D12.776.157.530.450.250.940 D12.776.157.530.937.952 D12.776.543.585.450.250.945 D12.776.543.585.937.975 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000075703 | ||||||
| Scope note: | A zinc efflux transporter highly expressed by ISLET CELLS of the pancreas. It functions in the accumulation of zinc in intracellular vesicles and may be involved in INSULIN maturation and storage processes. Variations in the SLC30A8 gene are associated with susceptibility to DIABETES MELLITUS, TYPE 2. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Cation Transport Proteins (2004-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57088 | ||||||
| Unique ID: | D000075703 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/06/29 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Zinc Transporter 8
- Preferred
| Concept UI |
M000631332 |
| Scope note | A zinc efflux transporter highly expressed by ISLET CELLS of the pancreas. It functions in the accumulation of zinc in intracellular vesicles and may be involved in INSULIN maturation and storage processes. Variations in the SLC30A8 gene are associated with susceptibility to DIABETES MELLITUS, TYPE 2. |
| Preferred term | Zinc Transporter 8 |
| Entry term(s) |
Slc30A8 Protein Solute Carrier Family 30 Member 8 Protein ZnT 8 Protein ZnT-8 Protein |
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