| Descriptor English: | Serotonin Plasma Membrane Transport Proteins | ||||||
| Descriptor Spanish: |
Proteínas de Transporte de Serotonina en la Membrana Plasmática
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| Descriptor Portuguese: | Proteínas da Membrana Plasmática de Transporte de Serotonina | ||||||
| Descriptor French: | Transporteurs de la sérotonine | ||||||
| Entry term(s): |
5 Hydroxytryptamine Plasma Membrane Transport Protein 5-Hydroxytryptamine Plasma Membrane Transport Protein 5HT Transporter Neurotransmitter Transport Proteins, Serotonin Specific Neurotransmitter Transport Proteins, Serotonin-Specific Neurotransmitter Transporters, Serotonin Specific Neurotransmitter Transporters, Serotonin-Specific Platelet Serotonin Transporter Platelets Serotonin Transporter SERT Proteins SLC6A4 Protein Serotonectin Serotonin Plasma Membrane Transporter Proteins Serotonin Transporter Serotonin Transporter, Platelet Serotonin Transporter, Platelets Serotonin Transporter, Sodium-Dependent Serotonin-Specific Neurotransmitter Transporters Sodium Dependent Serotonin Transporter Sodium-Dependent Serotonin Transporter Solute Carrier Family 6, Member 4 Protein Transporter, Sodium-Dependent Serotonin |
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| Tree number(s): |
D12.776.157.530.450.625.311 D12.776.157.530.562.374.875 D12.776.157.530.937.624 D12.776.543.585.450.625.374 D12.776.543.585.562.374.875 D12.776.543.585.937.747 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050486 | ||||||
| Scope note: | Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
antagonists & inhibitors:Serotonin Uptake Inhibitors
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| Previous Indexing: |
Carrier Proteins (1992-2004) Membrane Glycoproteins (1992-2005) Membrane Transport Proteins (2005) Nerve Tissue Proteins (1992-2005) |
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| Public MeSH Note: | 2006; SEROTONIN TRANSPORTER was indexed under MEMBRANE TRANSPORT PROTEINS 2005, MEMBRANE GLYCOPROTEINS, NERVE TISSUE PROTEINS & MEMBRANE TRANSPORT PROTEINS 1992-2005, CARRIER PROTEINS 1992-2004; SEROTONECTIN was indexed under CARRIER PROTEINS 1983-2005 |
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| History Note: | 2006(1992) |
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| Related: |
Receptors, Serotonin
MeSH | ||||||
| DeCS ID: | 50907 | ||||||
| Unique ID: | D050486 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2016/02/26 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Serotonin Plasma Membrane Transport Proteins
- Preferred
Solute Carrier Family 6, Member 4 Protein
- Narrower
Serotonectin
- Narrower
| Concept UI |
M0475614 |
| Scope note | Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS. |
| Preferred term | Serotonin Plasma Membrane Transport Proteins |
| Entry term(s) |
5 Hydroxytryptamine Plasma Membrane Transport Protein 5-Hydroxytryptamine Plasma Membrane Transport Protein Neurotransmitter Transport Proteins, Serotonin Specific Neurotransmitter Transport Proteins, Serotonin-Specific Neurotransmitter Transporters, Serotonin Specific Neurotransmitter Transporters, Serotonin-Specific SERT Proteins Serotonin Plasma Membrane Transporter Proteins Serotonin Transporter Serotonin-Specific Neurotransmitter Transporters |
| Concept UI |
M000614358 |
| Preferred term | Solute Carrier Family 6, Member 4 Protein |
| Entry term(s) |
5HT Transporter SLC6A4 Protein Serotonin Transporter, Sodium-Dependent Sodium Dependent Serotonin Transporter Sodium-Dependent Serotonin Transporter Transporter, Sodium-Dependent Serotonin |
| Concept UI |
M0117243 |
| Scope note | A sodium chloride-dependent neurotransmitter symporter located on the PLASMA MEMBRANE of BLOOD PLATELETS. It transports SEROTONIN from the EXTRACELLULAR SPACE into the platelet CYTOPLASM. |
| Preferred term | Serotonectin |
| Entry term(s) |
Platelet Serotonin Transporter Platelets Serotonin Transporter Serotonin Transporter, Platelet Serotonin Transporter, Platelets |
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