| Descriptor English: | Zinc Finger Protein Gli2 | ||||||
| Descriptor Spanish: |
Proteína Gli2 con Dedos de Zinc
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| Descriptor Portuguese: | Proteína Gli2 com Dedos de Zinco | ||||||
| Descriptor French: | Protéine à doigts de zinc Gli2 | ||||||
| Entry term(s): |
Gli2 Protein |
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| Tree number(s): |
D12.776.260.755.925 D12.776.930.900.850 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000075746 | ||||||
| Scope note: | A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2018; see GLI2 PROTEIN 1997-2017; ZINC FINGER PROTEIN GLI2 was indexed under KRUPPEL-LIKE TRANSCRIPTION FACTORS 2006-2017; under TRANSCRIPTION FACTORS 1999-2005; and under PROTEINS 1997-1998 |
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| History Note: | 2018 (1997); use GLI2 PROTEIN 1997-2017 |
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| Related: |
Hedgehog Proteins
MeSH | ||||||
| DeCS ID: | 57120 | ||||||
| Unique ID: | D000075746 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/06/29 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Zinc Finger Protein Gli2
- Preferred
| Concept UI |
M000631360 |
| Scope note | A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME. |
| Preferred term | Zinc Finger Protein Gli2 |
| Entry term(s) |
Gli2 Protein |
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