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Descriptor English: Kruppel-Like Factor 6
Descriptor Spanish: Factor 6 Similar a Kruppel
Descriptor factor 6 similar a Kruppel
Entry term(s) Proteína COPEB
proteína CPBP
proteína de unión al elemento promotor central
Scope note: Factor de transcripción similar a Kruppel que contiene tres DEDOS DE ZINC CYS2-HIS2 en el extremo C y se une a una SECUENCIA RICA EN GC (caja GC) en los promotores ascendentes del gen. Funciona como activador transcripcional, supresor tumoral y en la regulación del crecimiento y desarrollo de los linfocitos B.
Descriptor Portuguese: Fator 6 Semelhante a Kruppel
Descriptor French: Facteur-6 de type krüppel
Entry term(s): COPEB Protein
CPBP Protein
Core Promoter Element Binding Protein
Kruppel Like Factor 6
Tree number(s): D12.776.260.522.563
D12.776.260.755.050
D12.776.624.664.700.120
D12.776.930.375.563
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075723
Scope note: A Kruppel-like transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS and binds to GC RICH SEQUENCE (GC box) in upstream gene promoters. It functions as a transcriptional activator, tumor suppressor, and may regulate growth and development of B-cells.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Kruppel-Like Transcription Factors (2006-2017)
Proto-Oncogene Proteins (1997-2017)
Trans-Activators (1997-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57114
Unique ID: D000075723
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29
Kruppel-Like Factor 6 - Preferred
Concept UI M000631304
Scope note A Kruppel-like transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS and binds to GC RICH SEQUENCE (GC box) in upstream gene promoters. It functions as a transcriptional activator, tumor suppressor, and may regulate growth and development of B-cells.
Preferred term Kruppel-Like Factor 6
Entry term(s) COPEB Protein
CPBP Protein
Core Promoter Element Binding Protein
Kruppel Like Factor 6



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