Search
Descriptor English: AAA Domain
Descriptor Spanish: Dominio AAA
Descriptor dominio AAA
Entry term(s) bucle A
bucle P
bucle-A
bucle-P
bucles A
dominio AAA+
dominios AAA
dominios AAA+
motivo Walker
motivo Walker A
motivo Walker B
motivos Walker
módulo AAA
módulo AAA+
módulos AAA
módulos AAA+
Scope note: Dominio de unos 250 aminoácidos común a las ATPasas AAA y a las proteínas AAA. Consta de un subdominio ATPasa con bucle P en el extremo N-terminal altamente conservado con una conformación alfa-beta-alfa y de un subdominio C-terminal menos conservado con una conformación todo alfa. El subdominio N-terminal incluye los motivos Walker A y Walker B, que sirven para la unión y la hidrólisis del ATP.
Descriptor Portuguese: Domínio AAA
Descriptor French: Domaine AAA
Entry term(s): A Loop
A Motif, Walker
A-Loop
A-Loops
AAA Domains
AAA Module
AAA Modules
AAA+ Domain
AAA+ Domains
AAA+ Module
AAA+ Modules
B Motif, Walker
Domain, AAA
Domain, AAA+
Domains, AAA
Domains, AAA+
Module, AAA
Module, AAA+
Modules, AAA
Modules, AAA+
Motif, Walker
Motif, Walker A
Motif, Walker B
Motifs, Walker
P Loop
P-Loop
P-Loops
Walker A Motif
Walker B Motif
Walker Motif
Walker Motifs
Tree number(s): G02.111.570.820.709.275.500.913
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074182
Scope note: An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Amino Acid Sequence (1990-2017)
Public MeSH Note: 2018
History Note: 2018
Related: ATPases Associated with Diverse Cellular Activities MeSH
DeCS ID: 57252
Unique ID: D000074182
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/02/24
AAA Domain - Preferred
Concept UI M000626136
Scope note An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
Preferred term AAA Domain
Entry term(s) AAA Domains
AAA Module
AAA Modules
AAA+ Domain
AAA+ Domains
AAA+ Module
AAA+ Modules
Domain, AAA
Domain, AAA+
Domains, AAA
Domains, AAA+
Module, AAA
Module, AAA+
Modules, AAA
Modules, AAA+
Walker Motifs - Narrower
Concept UI M000625780
Scope note Highly conserved amino acid motifs that occur in ATP-binding proteins, especially AAA ATPases. They are characterized by the pattern G-x(4)-GK-[TS]; G, K, T and S are GLYCINE; LYSINE; THREONINE; and SERINE, where x can be any amino acid. This motif binds the beta-phosphate of nucleotides.
Preferred term Walker Motifs
Entry term(s) Motif, Walker
Motifs, Walker
P Loop
P-Loop
P-Loops
Walker Motif
A-Loop - Related but not broader or narrower
Concept UI M000625783
Preferred term A-Loop
Entry term(s) A Loop
A-Loops
Walker B Motif - Narrower
Concept UI M000625782
Preferred term Walker B Motif
Entry term(s) B Motif, Walker
Motif, Walker B
Walker A Motif - Narrower
Concept UI M000625781
Preferred term Walker A Motif
Entry term(s) A Motif, Walker
Motif, Walker A



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey