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Descriptor English: Ertapenem
Descriptor Spanish: Ertapenem
Descriptor ertapenem
Entry term(s) Invanoz
Invanz
ertapenem sódico
Scope note: Antibacteriano derivado carbapenémico que es más estable con respecto a la deshidropeptidasa I renal que el IMIPENEM, pero que no necesita administrarse con un inhibidor de la enzima como la CILASTATINA. Se usa en el tratamiento de infecciones por bacterias grampositivas y gramnegativas tales como infecciones intraabdominales, infecciones ginecológicas agudas, infecciones urinarias complicadas, infecciones cutáneas e infecciones respiratorias. También se usa para prevenir las infecciones en la cirugía colorrectal.
Descriptor Portuguese: Ertapenem
Descriptor French: Ertapénem
Entry term(s): Ertapenem Sodium
Invanoz
Invanz
Tree number(s): D02.065.589.099.124.225
D03.633.100.300.124.225
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077727
Scope note: A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of Gram-positive and Gram-negative bacterial infections including intra-abdominal infections, acute gynecological infections, complicated urinary tract infections, skin infections, and respiratory tract infections. It is also used to prevent infection in colorectal surgery.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Registry Number: G32F6EID2H
CAS Type 1 Name: (4R,5R,6S)-3-((3S,5S)-5-((3-Carboxyphenyl)carbamoyl)pyrrolidin-3-yl)sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
Public MeSH Note: 2019; ERTAPENEM was indexed under BETA-LACTAMS 2006-2018; and under LACTAMS 2002-2005
History Note: 2019 (2002)
DeCS ID: 57734
Unique ID: D000077727
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03
Ertapenem - Preferred
Concept UI M0414190
Scope note A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of Gram-positive and Gram-negative bacterial infections including intra-abdominal infections, acute gynecological infections, complicated urinary tract infections, skin infections, and respiratory tract infections. It is also used to prevent infection in colorectal surgery.
Preferred term Ertapenem
Invanoz - Narrower
Concept UI M0477785
Preferred term Invanoz
Invanz - Narrower
Concept UI M0477786
Preferred term Invanz
Ertapenem Sodium - Narrower
Concept UI M0477784
Preferred term Ertapenem Sodium



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