| Descriptor English: | Tripeptidyl-Peptidase 1 | ||||||
| Descriptor Spanish: |
Tripeptidil Peptidasa 1
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| Descriptor Portuguese: | Tripeptidil-Peptidase 1 | ||||||
| Descriptor French: | Tripeptidyl-peptidase-1 | ||||||
| Entry term(s): |
1, Tripeptidyl-Peptidase CLN2 Protein I, Tripeptidyl Peptidase I, Tripeptidyl Protease I, Tripeptidyl-Peptidase Peptidase I, Tripeptidyl Protein, CLN2 Protein, TPP1 TPP1 Protein Tripeptidyl Aminopeptidase I Tripeptidyl Peptidase I Tripeptidyl Protease I Tripeptidyl-Peptidase I |
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| Tree number(s): |
D08.811.277.656.350.100.877 D08.811.277.656.350.350.843 D08.811.277.656.959.780 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000091346 | ||||||
| Scope note: | Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE CEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2022; TRIPEPTIDYL-PEPTIDASES 1 was indexed under AMINOPEPTIDASES, DIPEPTIDYL-PEPTIDYL-PEPTIDASES and under SERINE PROTEASES 1995-2021 |
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| History Note: | 2022 (1993) |
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| DeCS ID: | 59867 | ||||||
| Unique ID: | D000091346 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2022/01/01 | ||||||
| Date of Entry: | 2021/07/09 | ||||||
| Revision Date: | 2021/07/01 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Tripeptidyl-Peptidase 1
- Preferred
| Concept UI |
M000748625 |
| Scope note | Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE CEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7. |
| Preferred term | Tripeptidyl-Peptidase 1 |
| Entry term(s) |
1, Tripeptidyl-Peptidase CLN2 Protein I, Tripeptidyl Peptidase I, Tripeptidyl Protease I, Tripeptidyl-Peptidase Peptidase I, Tripeptidyl Protein, CLN2 Protein, TPP1 TPP1 Protein Tripeptidyl Aminopeptidase I Tripeptidyl Peptidase I Tripeptidyl Protease I Tripeptidyl-Peptidase I |
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