Search
Descriptor English: Bisbenzimidazole
Descriptor Spanish: Bisbenzimidazol
Descriptor Portuguese: Bisbenzimidazol
Descriptor French: Bisbenzimide
Entry term(s): 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimidazole Trihydrochloride
Bisbenzimide
Hoe 33258
Hoe-33258
Hoe33258
Hoechst 33258
NSC 322921
NSC-322921
NSC322921
Pibenzimol
Tree number(s): D03.633.100.103.145
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006690
Scope note: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Filaricides
Fluorescent Dyes
Registry Number: LHQ7J5KV9B
CAS Type 1 Name: 4-(5-(5-(4-Methylpiperazin-1-yl)benzimidazol-2- yl)benzimidazol-2-yl)phenol
Previous Indexing: Benzimidazoles (1971-1976)
Phenols (1972-1975)
Piperazines (1971-1975)
Public MeSH Note: 2008; see BISBENZIMIDE 1991-2008, see BENZIMIDAZOLES 1977-1990
History Note: 2008(1977)
DeCS ID: 6845
Unique ID: D006690
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/13
Revision Date: 2016/05/27
Bisbenzimidazole - Preferred
Concept UI M0515726
Scope note A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Preferred term Bisbenzimidazole
Entry term(s) Pibenzimol
NSC-322921 - Narrower
Concept UI M0353557
Preferred term NSC-322921
Entry term(s) NSC 322921
NSC322921
Bisbenzimidazole Trihydrochloride - Narrower
Concept UI M0010486
Preferred term Bisbenzimidazole Trihydrochloride
Entry term(s) 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimide
Hoechst 33258 - Narrower
Concept UI M0353558
Preferred term Hoechst 33258
Entry term(s) Hoe 33258
Hoe-33258
Hoe33258



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey