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Descriptor English: Bisbenzimidazole
Descriptor Spanish: Bisbenzimidazol
Descriptor bisbencimidazol
Entry term(s) bisbencimida
bisbenzimida
Scope note: Bencimidazol que es un agente antifilaria. Cuando se une a determinados nucleótidos en el ADN es fluorescente, por lo que constituye una útil herramienta para el estudio de la replicación de ADN. Esta sustancia también interfiere con la mitosis.
Descriptor Portuguese: Bisbenzimidazol
Descriptor French: Bisbenzimide
Entry term(s): 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimidazole Trihydrochloride
Bisbenzimide
Hoe 33258
Hoe-33258
Hoe33258
Hoechst 33258
NSC 322921
NSC-322921
NSC322921
Pibenzimol
Tree number(s): D03.633.100.103.145
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006690
Scope note: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Filaricides
Fluorescent Dyes
Registry Number: LHQ7J5KV9B
CAS Type 1 Name: 4-(5-(5-(4-Methylpiperazin-1-yl)benzimidazol-2- yl)benzimidazol-2-yl)phenol
Previous Indexing: Benzimidazoles (1971-1976)
Phenols (1972-1975)
Piperazines (1971-1975)
Public MeSH Note: 2008; see BISBENZIMIDE 1991-2008, see BENZIMIDAZOLES 1977-1990
History Note: 2008(1977)
DeCS ID: 6845
Unique ID: D006690
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/13
Revision Date: 2016/05/27
Bisbenzimidazole - Preferred
Concept UI M0515726
Scope note A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Preferred term Bisbenzimidazole
Entry term(s) Pibenzimol
NSC-322921 - Narrower
Concept UI M0353557
Preferred term NSC-322921
Entry term(s) NSC 322921
NSC322921
Bisbenzimidazole Trihydrochloride - Narrower
Concept UI M0010486
Preferred term Bisbenzimidazole Trihydrochloride
Entry term(s) 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimide
Hoechst 33258 - Narrower
Concept UI M0353558
Preferred term Hoechst 33258
Entry term(s) Hoe 33258
Hoe-33258
Hoe33258



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