| Descriptor English: | Irritants | ||||||
| Descriptor Spanish: | 
                                Irritantes                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Irritantes | ||||||
| Descriptor French: | Irritants | ||||||
| Entry term(s): | 
                                    Counterirritant Counterirritants Irritant Pustulant Pustulants Rubefacient Rubefacients Vesicant Vesicants  | 
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| Tree number(s): | 
                                        D27.720.400 D27.888.569.300  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007509 | ||||||
| Scope note: | Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants. | 
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| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Online Note: | use IRRITANTS to search RUBEFACIENTS & VESICANTS 1966-79 | 
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| History Note: | RUBEFACIENTS & VESICANTS were see under IRRITANTS 1963-79 | 
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| DeCS ID: | 7676 | ||||||
| Unique ID: | D007509 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1960/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2020/05/27 | 
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                                        CHEMICALS AND DRUGS
 
Chemical Actions and Uses [D27]Chemical Actions and Uses - 
                                    
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses 
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                                                             | 
                                
                        
                                                                    
                        Irritants                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Vesicants                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Counterirritants                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                                                                    
                        Rubefacients                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Pustulants                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0011729 | 
                                
| Scope note | Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants. | 
| Preferred term | Irritants | 
| Entry term(s) | 
                                        
                                                                                            Irritant                                                 | 
                                
| Concept UI | 
                                        
                                        M0011732 | 
                                
| Preferred term | Vesicants | 
| Entry term(s) | 
                                        
                                                                                            Vesicant                                                 | 
                                
| Concept UI | 
                                        
                                        M0011728 | 
                                
| Preferred term | Counterirritants | 
| Entry term(s) | 
                                        
                                                                                            Counterirritant                                                 | 
                                
| Concept UI | 
                                        
                                        M0011731 | 
                                
| Preferred term | Rubefacients | 
| Entry term(s) | 
                                        
                                                                                            Rubefacient                                                 | 
                                
| Concept UI | 
                                        
                                        M0011730 | 
                                
| Preferred term | Pustulants | 
| Entry term(s) | 
                                        
                                                                                            Pustulant                                                 | 
                                
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