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Descriptor English: Ketamine
Descriptor Spanish: Ketamina
Descriptor Portuguese: Ketamina
Descriptor French: Kétamine
Entry term(s): 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
CI 581
CI-581
CI581
Calipsol
Calypsol
Kalipsol
Ketalar
Ketamine Hydrochloride
Ketanest
Ketaset
Tree number(s): D02.455.426.392.368.367.652
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007649
Scope note: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Analgesics
Anesthetics, Dissociative
Excitatory Amino Acid Antagonists
Registry Number: 690G0D6V8H
CAS Type 1 Name: Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)-
Previous Indexing: Analgesics (1966-1971)
Anesthetics (1972)
Cyclohexanes (1968-1972)
Public MeSH Note: 73
Online Note: use KETAMINE to search CI-581 1969-72 (as Prov)
History Note: 73; was CI-581 1969-72 (Prov)
DeCS ID: 7815
Unique ID: D007649
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Ketamine - Preferred
Concept UI M0011982
Scope note A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
Preferred term Ketamine
Entry term(s) 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
CI-581 - Narrower
Concept UI M0011980
Preferred term CI-581
Entry term(s) CI 581
CI581
Ketalar - Narrower
Concept UI M0011981
Preferred term Ketalar
Ketaset - Narrower
Concept UI M0351821
Preferred term Ketaset
Ketanest - Narrower
Concept UI M0351822
Preferred term Ketanest
Calipsol - Narrower
Concept UI M0351824
Preferred term Calipsol
Entry term(s) Calypsol
Kalipsol
Ketamine Hydrochloride - Narrower
Concept UI M0351823
Preferred term Ketamine Hydrochloride



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