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Descriptor English: Leukocidins
Descriptor Spanish: Leucocidinas
Descriptor leucocidinas
Scope note: Sustancias tóxicas para los LEUCOCITOS. Son EXOTOXINAS producidas por algunos STAPHYLOCOCCUS y STREPTOCOCCUS patógenos, que destruyen leucocitos mediante lisis de los granulos citoplasmáticos y son parcialmente responsables de la patogenicidad de los organismos.
Descriptor Portuguese: Leucocidinas
Descriptor French: Leucocidine
Entry term(s): Leucocidin
Leukocidin
Leukocidin Proteins
Proteins, Leukocidin
Tree number(s): D12.776.543.695.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007956
Scope note: Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
Annotation: /antag permitted but consider also ANTITOXINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Cytotoxins
Public MeSH Note: 78; was LEUKOCIDIN 1965-77
Online Note: use LEUKOCIDINS to search LEUKOCIDIN 1966-77
History Note: 78; was LEUKOCIDIN 1965-77
DeCS ID: 8134
Unique ID: D007956
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2006/07/05
Leukocidins - Preferred
Concept UI M0012402
Scope note Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
Preferred term Leukocidins
Entry term(s) Leukocidin Proteins
Proteins, Leukocidin
Leukocidin - Narrower
Concept UI M0012401
Preferred term Leukocidin
Entry term(s) Leucocidin



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