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Descriptor in English: Mercaptopurine
Descriptor in Spanish: Mercaptopurina
Descriptor in Portuguese: Mercaptopurina
Descriptor in French: Mercaptopurine
Entry term(s): 1,7-Dihydro-6H-purine-6-thione
6 Mercaptopurine
6 Mercaptopurine Monohydrate
6 Thiohypoxanthine
6 Thiopurine
6-Mercaptopurine
6-Mercaptopurine Monohydrate
6-Thiohypoxanthine
6-Thiopurine
6H-Purine-6-thione, 1,7-dihydro-
BW 57 323H
BW 57-323H
BW 57323H
Leupurin
Mecaptopurine Anhydrous
Mercaptopurina Wellcome
Puri-Nethol
Purimethol
Purinethol
Tree number(s): D02.886.489.534
D03.633.100.759.570
Scope note: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2018(1985)
DeCS UI: 8800
Descriptor UI: D015122
Date Established: 1985/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/05
Mercaptopurine - Preferred
Concept UI M0023263
Scope note An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Preferred term Mercaptopurine
Entry term(s) 1,7-Dihydro-6H-purine-6-thione
6 Mercaptopurine
6 Mercaptopurine Monohydrate
6 Thiohypoxanthine
6 Thiopurine
6-Mercaptopurine
6-Mercaptopurine Monohydrate
6-Thiohypoxanthine
6-Thiopurine
6H-Purine-6-thione, 1,7-dihydro-
Purinethol - Narrower
Concept UI M0352351
Preferred term Purinethol
Entry term(s) Puri-Nethol
Mercaptopurina Wellcome - Narrower
Concept UI M0474764
Preferred term Mercaptopurina Wellcome
Leupurin - Narrower
Concept UI M0352353
Preferred term Leupurin
BW 57-323H - Narrower
Concept UI M0352354
Preferred term BW 57-323H
Entry term(s) BW 57 323H
BW 57323H
Purimethol - Narrower
Concept UI M0352352
Preferred term Purimethol
Mecaptopurine Anhydrous - Related but not broader or narrower
Concept UI M000618306
Preferred term Mecaptopurine Anhydrous



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