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Descriptor English: Pyrroline Carboxylate Reductases
Descriptor Spanish: Pirrolina Carboxilato Reductasas
Descriptor pirrolina carboxilato reductasas
Scope note: Grupo de enzimas que catalizan la reducción de la 1-pirrolina carboxilato a prolina en presencia de NAD(P)H. Comprende tanto la 2-oxidorreductasa (EC 1.5.1.1) como la 5-oxidorreductasa (EC 1.5.1.2). La primera también reduce la 1-piperidina-2-carboxilato a pipecolato y la última también reduce la 1-pirrolina-3-hidroxi-5-carboxilato a hidroxiprolina.
Descriptor Portuguese: Pirrolina Carboxilato Redutases
Descriptor French: Pyrroline carboxylate reductases
Entry term(s): Carboxylate Reductases, Pyrroline
Reductases, Pyrroline Carboxylate
Tree number(s): D08.811.682.662.695
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011762
Scope note: A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.5.1.-
Previous Indexing: Amine Oxidoreductases (1975-1976)
Oxidoreductases (1966-1974)
Public MeSH Note: 91; was see under AMINE OXIDOREDUCTASES 1977-90
History Note: 91(77); was see under AMINE OXIDOREDUCTASES 1977-90
DeCS ID: 12199
Unique ID: D011762
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/05/19
Revision Date: 2005/06/30
Pyrroline Carboxylate Reductases - Preferred
Concept UI M0018282
Scope note A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
Preferred term Pyrroline Carboxylate Reductases
Entry term(s) Carboxylate Reductases, Pyrroline
Reductases, Pyrroline Carboxylate



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