| Descriptor English: | mu-Crystallins | ||||||
| Descriptor Spanish: |
Cristalinas mu
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| Descriptor Portuguese: | Cristalinas mu | ||||||
| Descriptor French: | Cristallines-mu | ||||||
| Entry term(s): |
CRYM Protein Crystallin mu Ketimine Reductase mu Crystallin Ketimine Reductase mu-Crystallin NADP Regulated Thyroid Hormone Binding Protein NADP-Regulated Thyroid Hormone Binding Protein Protein, CRYM Protein, THBP Reductase mu-Crystallin, Ketimine THBP Protein mu Crystallins mu, Crystallin mu-Crystallin, Ketimine Reductase |
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| Tree number(s): |
D08.811.682.662.436 D12.776.306.366.888 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000090803 | ||||||
| Scope note: | A subclass of crystallins expressed highly in lens of diurnal Australian MARSUPIALS and in neural tissue, muscle, and kidney in humans. It is not a structural protein accounting for the transparency of the human lens unlike other crystallins but instead plays a role in thyroid hormone bioavailability. It is also a cerebral ketimine reductase which reduces cyclic imines (e.g., DELTA(1)-PIPERIDINE-2-CARBOXYLIC ACID; CYSTATHIONINE KETIMINE and LANTHIONINE KETIMINE) in mammalian brain. Mutations in mu-crystallins are associated with an autosomal dominant NONSYNDROMIC DEAFNESS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 1.5.1.25 | ||||||
| Public MeSH Note: | 2022; for CRYSTALLIN MU see under CRYSTALLINS (1992-2021) |
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| History Note: | 2022(1992) |
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| DeCS ID: | 59821 | ||||||
| Unique ID: | D000090803 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2022/01/01 | ||||||
| Date of Entry: | 2021/07/09 | ||||||
| Revision Date: | 2021/06/30 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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mu-Crystallins
- Preferred
| Concept UI |
M000747331 |
| Scope note | A subclass of crystallins expressed highly in lens of diurnal Australian MARSUPIALS and in neural tissue, muscle, and kidney in humans. It is not a structural protein accounting for the transparency of the human lens unlike other crystallins but instead plays a role in thyroid hormone bioavailability. It is also a cerebral ketimine reductase which reduces cyclic imines (e.g., DELTA(1)-PIPERIDINE-2-CARBOXYLIC ACID; CYSTATHIONINE KETIMINE and LANTHIONINE KETIMINE) in mammalian brain. Mutations in mu-crystallins are associated with an autosomal dominant NONSYNDROMIC DEAFNESS. |
| Preferred term | mu-Crystallins |
| Entry term(s) |
CRYM Protein Crystallin mu Ketimine Reductase mu Crystallin Ketimine Reductase mu-Crystallin NADP Regulated Thyroid Hormone Binding Protein NADP-Regulated Thyroid Hormone Binding Protein Protein, CRYM Protein, THBP Reductase mu-Crystallin, Ketimine THBP Protein mu Crystallins mu, Crystallin mu-Crystallin, Ketimine Reductase |
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