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Descriptor English: Saccharopine Dehydrogenases
Descriptor Spanish: Sacaropina Deshidrogenasas
Descriptor sacaropina deshidrogenasas
Entry term(s) lisina-2-oxoglutarato-reductasa
sacaropina-deshidrogenasa
sacaropina-deshidrogenasa (NAD+, formadora de L-glutamato)
sacaropina-deshidrogenasa (NAD+, formadora de L-lisina)
sacaropina-deshidrogenasa (NADP+, formadora de L-glutamato)
sacaropina-deshidrogenasa (NADP+, formadora de L-lisina)
Scope note: Amino oxidoreductasas que utilizan NAD+ (EC 1.5.1.7) o NADP+ (EC 1.5.1.8) como aceptor para formar LISINA o NAD+ (EC 1.5.1.9) o NADP+ (EC 1.5.1.10) como aceptor para formar L-GLUTAMATO. La deficiencia de esta enzima causa las HIPERLISINEMIAS.
Descriptor Portuguese: Sacaropina Desidrogenases
Descriptor French: Saccharopine dehydrogenases
Entry term(s): Dehydrogenases, Saccharopine
Lysine 2 Oxoglutarate Reductase
Lysine Ketoglutarate Reductase
Lysine-2-Oxoglutarate Reductase
Lysine-Ketoglutarate Reductase
Reductase, Lysine-2-Oxoglutarate
Reductase, Lysine-Ketoglutarate
Saccharopine Dehydrogenase
Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming)
Saccharopine Dehydrogenase (NAD+, L-Lysine Forming)
Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming)
Saccharopine Dehydrogenase (NADP+, L-Lysine Forming)
Tree number(s): D08.811.682.662.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012443
Scope note: Amine oxidoreductases that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS.
Annotation: /defic: consider also HYPERLYSINEMIAS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.5.1.-
Previous Indexing: Ketoglutaric Acids (1972-1974)
Lysine (1970-1974)
Oxidoreductases (1970-1974)
Public MeSH Note: 91; was see under AMINE OXIDOREDUCTASES 1975-90
History Note: 91(75); was see under AMINE OXIDOREDUCTASES 1975-90
Related: Hyperlysinemias MeSH
DeCS ID: 12819
Unique ID: D012443
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2005/06/30
Saccharopine Dehydrogenases - Preferred
Concept UI M0019332
Scope note Amine oxidoreductases that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS.
Preferred term Saccharopine Dehydrogenases
Entry term(s) Dehydrogenases, Saccharopine
Lysine Ketoglutarate Reductase
Lysine-Ketoglutarate Reductase
Reductase, Lysine-Ketoglutarate
Saccharopine Dehydrogenase
Saccharopine Dehydrogenase (NADP+, L-Lysine Forming) - Narrower
Concept UI M0456329
Preferred term Saccharopine Dehydrogenase (NADP+, L-Lysine Forming)
Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming) - Narrower
Concept UI M0456331
Preferred term Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming)
Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming) - Narrower
Concept UI M0456330
Preferred term Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming)
Saccharopine Dehydrogenase (NAD+, L-Lysine Forming) - Narrower
Concept UI M0456328
Preferred term Saccharopine Dehydrogenase (NAD+, L-Lysine Forming)
Entry term(s) Lysine 2 Oxoglutarate Reductase
Lysine-2-Oxoglutarate Reductase
Reductase, Lysine-2-Oxoglutarate



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