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Descriptor in English: Quinidine
Descriptor in Spanish: Quinidina
Descriptor in Portuguese: Quinidina
Descriptor in French: Quinidine
Entry term(s): Adaquin
Apo Quinidine
Apo-Quinidine
Chinidin
Quincardine
Quinidex
Quinidine Sulfate
Quinora
Sulfate, Quinidine
Tree number(s): D03.132.206.636
D03.605.687.637
D03.633.100.810.699
Scope note: An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
DeCS UI: 12239
Descriptor UI: D011802
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Quinidine - Preferred
Concept UI M0018341
Scope note An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
Preferred term Quinidine
Entry term(s) Chinidin
Apo-Quinidine - Narrower
Concept UI M0474991
Preferred term Apo-Quinidine
Entry term(s) Apo Quinidine
Quinora - Narrower
Concept UI M0018343
Preferred term Quinora
Quinidex - Narrower
Concept UI M0474993
Preferred term Quinidex
Quinidine Sulfate - Narrower
Concept UI M0018342
Preferred term Quinidine Sulfate
Entry term(s) Sulfate, Quinidine
Adaquin - Narrower
Concept UI M0474990
Preferred term Adaquin
Quincardine - Narrower
Concept UI M0474992
Preferred term Quincardine



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