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Descriptor English: | Renin-Angiotensin System | ||||||
Descriptor Spanish: |
Sistema Renina-Angiotensina
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Descriptor Portuguese: | Sistema Renina-Angiotensina | ||||||
Descriptor French: | Système rénine-angiotensine | ||||||
Entry term(s): |
SRA (Système Rénine-Angiotensine) SRAA Système rénine-angiotensine-aldostérone |
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Tree number(s): |
G03.820 G09.330.380.813 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D012084 | ||||||
Scope note: | A BLOOD PRESSURE regulating system of interacting components that include RENIN; ANGIOTENSINOGEN; ANGIOTENSIN CONVERTING ENZYME; ANGIOTENSIN I; ANGIOTENSIN II; and angiotensinase. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming ANGIOTENSIN I. Angiotensin-converting enzyme, contained in the lung, acts on angiotensin I in the plasma converting it to ANGIOTENSIN II, an extremely powerful vasoconstrictor. Angiotensin II causes contraction of the arteriolar and renal VASCULAR SMOOTH MUSCLE, leading to retention of salt and water in the KIDNEY and increased arterial blood pressure. In addition, angiotensin II stimulates the release of ALDOSTERONE from the ADRENAL CORTEX, which in turn also increases salt and water retention in the kidney. Angiotensin-converting enzyme also breaks down BRADYKININ, a powerful vasodilator and component of the KALLIKREIN-KININ SYSTEM. |
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Annotation: | note entry term but do not index under ALDOSTERONE unless particularly discussed |
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Allowable Qualifiers: |
DE effets des médicaments et des substances chimiques GE génétique IM immunologie PH physiologie RE effets des radiations |
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Related: |
Inhibiteurs de l'enzyme de conversion de l'angiotensine
MeSH Système kallicréine-kinine MeSH | ||||||
DeCS ID: | 12506 | ||||||
Unique ID: | D012084 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1982/01/01 | ||||||
Date of Entry: | 1981/05/19 | ||||||
Revision Date: | 2016/07/01 |
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PHÉNOMÈNES ET PROCESSUS
Métabolisme [G03]Métabolisme
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Système rénine-angiotensine
- Preferred
Système rénine-angiotensine-aldostérone
- Broader
Concept UI |
M0018777 |
Preferred term | Système rénine-angiotensine |
Entry term(s) |
SRA (Système Rénine-Angiotensine) |
Concept UI |
M0018778 |
Preferred term | Système rénine-angiotensine-aldostérone |
Entry term(s) |
SRAA |
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