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Descriptor English: ATP Citrate (pro-S)-Lyase
Descriptor Spanish: ATP Citrato (pro-S)-Liasa
Descriptor ATP citrato (pro-S)-liasa
Entry term(s) ATP citrato liasa
ATP citrato sintasa
enzima de escisión de citrato
Scope note: Enzima que, en presencia de ATP y COENZIMA A, cataliza la escisión del citrato para dar lugar a acetil CoA, oxalacetato, ADP y ORTOFOSFATO. Esta reacción representa una etapa importante en la biosíntesis de los ácidos grasos. Esta enzima anteriormente se íncluyó en EC 4.1.3.8.
Descriptor Portuguese: ATP Citrato (pro-S)-Liase
Descriptor French: ATP citrate (pro-S)-lyase
Entry term(s): ATP Citrate (pro-3S)-Lyase
ATP Citrate Lyase
ATP Citrate Synthase
ATP Dependent Citrate Lyase
ATP-Dependent Citrate Lyase
Citrate Cleavage Enzyme
Citrate Lyase, ATP
Citrate Lyase, ATP-Dependent
Citrate Synthase, ATP
Cleavage Enzyme, Citrate
Lyase, ATP Citrate
Lyase, ATP-Dependent Citrate
Synthase, ATP Citrate
Tree number(s): D08.811.913.050.331
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001275
Scope note: An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.3.8
CAS Type 1 Name: ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating)
Previous Indexing: Lyases (1966-1972)
Public MeSH Note: 98; see ATP CITRATE LYASE 1977-97; see KETOACID-LYASES 1973-76
History Note: 98(73)
DeCS ID: 1282
Unique ID: D001275
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
ATP Citrate (pro-S)-Lyase - Preferred
Concept UI M0001918
Scope note An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.
Preferred term ATP Citrate (pro-S)-Lyase
Entry term(s) ATP Citrate (pro-3S)-Lyase
ATP Citrate Lyase
ATP Citrate Synthase
ATP Dependent Citrate Lyase
ATP-Dependent Citrate Lyase
Citrate Cleavage Enzyme
Citrate Lyase, ATP
Citrate Lyase, ATP-Dependent
Citrate Synthase, ATP
Cleavage Enzyme, Citrate
Lyase, ATP Citrate
Lyase, ATP-Dependent Citrate
Synthase, ATP Citrate



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