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Descriptor English: Citrate (si)-Synthase
Descriptor Spanish: Citrato (si)-Sintasa
Descriptor citrato (si)-sintasa
Entry term(s) citrato sintasa
Scope note: Enzima que cataliza el primer paso del ciclo del ácido tricarboxílico (CICLO DEL ACIDO CÍTRICO). Cataliza la reacción del oxaloacetato y el acetil CoA para formar citrato y coenzima A. Esta enzima fue listada anteriormente en EC 4.1.3.7.
Descriptor Portuguese: Citrato (si)-Sintase
Descriptor French: Citrate (si)-synthase
Entry term(s): Citrate Synthase
Synthase, Citrate
Tree number(s): D08.811.913.050.368
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002950
Scope note: Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.3.1
CAS Type 1 Name: Citrate oxaloacetate-lyase ((pro-3S)-CH2COO(-)--acetyl-CoA)
Public MeSH Note: 98; see CITRATE SYNTHASE 1991-97, see KETOACID-LYASES 1973-90
History Note: 98(73)
DeCS ID: 2976
Unique ID: D002950
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Citrate (si)-Synthase - Preferred
Concept UI M0004514
Scope note Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
Preferred term Citrate (si)-Synthase
Entry term(s) Citrate Synthase
Synthase, Citrate



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