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Descriptor in English: Cytochalasins
Descriptor in Spanish: Citocalasinas
Descriptor in Portuguese: Citocalasinas
Descriptor in French: Cytochalasines
Tree number(s): D03.633.100.473.231
D23.946.587.370
Scope note: 11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at the C10 position are called chaetoglobosins. They are produced by various fungi. Some members interact with ACTIN and inhibit CYTOKINESIS.
Annotation: /antag permitted but consider also ANTITOXINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 74(73)
DeCS UI: 3590
Descriptor UI: D003572
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Cytochalasins - Preferred
Concept UI M0005581
Scope note 11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at the C10 position are called chaetoglobosins. They are produced by various fungi. Some members interact with ACTIN and inhibit CYTOKINESIS.
Preferred term Cytochalasins



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