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Descriptor English: Venturicidins
Descriptor Spanish: Venturicidinas
Descriptor venturicidinas
Scope note: Sustancias tóxicas aisladas de varias cepas de Streptomyces. Son macrólidos de 20 miembros que inhiben la fosforilación oxidativa y ATPasas mitocondriales. Las venturicidinas A y B son glicósidos. Se utilizan principalmente en el estudio de la función mitocondrial.
Descriptor Portuguese: Venturicidinas
Descriptor French: Venturicidines
Tree number(s): D02.540.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014698
Scope note: Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function.
Annotation: uncoupling agents & antifungal antibiotics; from Streptomyces
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antifungal Agents
Uncoupling Agents
Previous Indexing: Antibiotics, Antifungal (1973-1976)
Glycosides (1973-1974)
Lactones (1973-1976)
Rhamnose (1973-1974)
Public MeSH Note: 91; was see under LACTONES 1977-90
History Note: 91(77); was see under LACTONES 1977-90
DeCS ID: 15103
Unique ID: D014698
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/16
Revision Date: 2009/07/06
Venturicidins - Preferred
Concept UI M0022603
Scope note Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function.
Preferred term Venturicidins



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