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Descriptor in English: Eplerenone
Descriptor in Spanish: Eplerenona
Descriptor in Portuguese: Eplerenona
Descriptor in French: Éplérénone
Entry term(s): 9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone
Eplerenon
Inspra
Tree number(s): D02.540.383
D04.210.500.745.745.329
Scope note: A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2019 (2000)
DeCS UI: 57670
Descriptor UI: D000077545
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Eplerenone - Preferred
Concept UI M0371594
Scope note A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.
Preferred term Eplerenone
Entry term(s) Eplerenon
Inspra - Narrower
Concept UI M0439953
Preferred term Inspra
9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone - Related but not broader or narrower
Concept UI M000640866
Preferred term 9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone



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