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Descriptor English: Gene Products, rev
Descriptor Spanish: Productos del Gen rev
Descriptor productos génicos rev
Entry term(s) productos de genes rev
proteína rev
Scope note: Proteínas nucleares que actúan en trans y cuya expresión funcional es necesaria para la replicación viral. En concreto, los productos del gen rev se necesitan para procesar y traducir los ARNm de gag y env; por tanto, rev regula la expresión de las proteínas estructurales del virus. También modula las proteínas reguladoras virales. Una secuencia antirrepresora que actúa en cis (CAR) en env, también conocida como elemento reactivo a rev (RRE), responde al producto del gen rev. El término rev es la abreviatura de regulador de viriones.
Descriptor Portuguese: Produtos do Gene rev
Descriptor French: Produits du gène rev
Entry term(s): Gene Product, rev
rev Gene Product
rev Gene Products
rev Protein
Tree number(s): D12.776.157.725.076
D12.776.664.962.186
D12.776.964.925.984.385
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015694
Scope note: Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. Rev is short for regulator of virion.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Retroviridae Proteins (1986-1989)
Viral Proteins (1986-1989)
Public MeSH Note: 91; was see under TRANS-ACTIVATORS 1990
History Note: 91(90); was see under TRANS-ACTIVATORS 1990
DeCS ID: 24678
Unique ID: D015694
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1989/07/06
Revision Date: 2007/07/09
Gene Products, rev - Preferred
Concept UI M0024072
Scope note Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. Rev is short for regulator of virion.
Preferred term Gene Products, rev
Entry term(s) Gene Product, rev
rev Gene Product
rev Gene Products
rev Protein



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