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Descriptor English: Fragile X Mental Retardation Protein
Descriptor Spanish: Proteína del Retraso Mental del Síndrome del Cromosoma X Frágil
Descriptor proteína del retraso mental del síndrome del cromosoma X frágil
Scope note: Proteína que se une al ARN y que se encuentra principalmente en el CITOPLASMA. Ayuda a regular la TRADUCCIÓN GENÉTICA en las NEURONAS y está ausente o infraexpresada en el SÍNDROME DEL CROMOSOMA X FRÁGIL.
Descriptor Portuguese: Proteína do X Frágil de Retardo Mental
Descriptor French: Protéine du syndrome X fragile
Entry term(s): FMRP Protein
Fragile X Mental Retardation 1 Protein
Fragile X Mental Retardation-1 Protein
Tree number(s): D12.776.157.725.061
D12.776.631.299
D12.776.664.962.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051860
Scope note: A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Fragile X Syndrome
Registry Number: 139135-51-6
Public MeSH Note: 2006; FRAGILE X MENTAL RETARDATION PROTEIN was indexed under NERVE TISSUE PROTEINS & RNA-BINDING PROTEINS 1991-2005
History Note: 2006(1991)
DeCS ID: 50923
Unique ID: D051860
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23
Fragile X Mental Retardation Protein - Preferred
Concept UI M0188653
Scope note A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
Preferred term Fragile X Mental Retardation Protein
Entry term(s) FMRP Protein
Fragile X Mental Retardation 1 Protein
Fragile X Mental Retardation-1 Protein



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