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Descriptor English: Indomethacin
Descriptor Spanish: Indometacina
Descriptor indometacina
Scope note: Antiinflamatorio no esteroideo (AINE) que inhibe la CICLOOXIGENASA, necesaria para la formación de PROSTAGLANDINAS y otros AUTACOIDES. También inhibe la motilidad de los LEUCOCITOS POLIMORFONUCLEARES.
Descriptor Portuguese: Indometacina
Descriptor French: Indométacine
Entry term(s): Amuno
Indocid
Indocin
Indomet 140
Indometacin
Indomethacin Hydrochloride
Metindol
Osmosin
Tree number(s): D03.633.100.473.420
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007213
Scope note: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Inflammatory Agents, Non-Steroidal
Cardiovascular Agents
Gout Suppressants
Tocolytic Agents
Cyclooxygenase Inhibitors
Registry Number: XXE1CET956
CAS Type 1 Name: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
Public MeSH Note: 1966
History Note: 1966 (1964)
DeCS ID: 28146
Unique ID: D007213
NLM Classification: QV 95
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/04/10
Indomethacin - Preferred
Concept UI M0011240
Scope note A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
Preferred term Indomethacin
Entry term(s) Indometacin
Osmosin - Narrower
Concept UI M0011241
Preferred term Osmosin
Indocid - Narrower
Concept UI M0011242
Preferred term Indocid
Metindol - Narrower
Concept UI M0353732
Preferred term Metindol
Indomet 140 - Narrower
Concept UI M0353733
Preferred term Indomet 140
Indomethacin Hydrochloride - Narrower
Concept UI M0330169
Preferred term Indomethacin Hydrochloride
Amuno - Narrower
Concept UI M0353728
Preferred term Amuno
Indocin - Narrower
Concept UI M0353731
Preferred term Indocin



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