Search
Descriptor English: Vemurafenib
Descriptor Spanish: Vemurafenib
Descriptor vemurafenib
Entry term(s) PLX 4032
PLX4032
R05185426
RG 7204
RG-7204
RG7204
Zelboraf
Scope note: Compuesto de indol y sulfonamida e inhibidor de las PROTEÍNAS PROTOONCOGÉNICAS B-RAF que se usa para el tratamiento del MELANOMA irresecable o metastásico.
Descriptor Portuguese: Vemurafenib
Descriptor French: Vémurafénib
Entry term(s): PLX 4032
PLX4032
R05185426
RG 7204
RG-7204
RG7204
Zelboraf
Tree number(s): D02.065.884.919
D02.886.590.700.919
D03.633.100.473.936
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077484
Scope note: An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic MELANOMA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number: 207SMY3FQT
CAS Type 1 Name: 1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-
Public MeSH Note: 2019; VEMURAFENIB was indexed under INDOLES and SULFONAMIDES 2010-2018
History Note: 2019 (2010)
DeCS ID: 57657
Unique ID: D000077484
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Vemurafenib - Preferred
Concept UI M0558887
Scope note An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic MELANOMA.
Preferred term Vemurafenib
PLX4032 - Narrower
Concept UI M0548744
Preferred term PLX4032
Entry term(s) PLX 4032
RG7204 - Narrower
Concept UI M000623499
Preferred term RG7204
Entry term(s) RG 7204
RG-7204
Zelboraf - Narrower
Concept UI M0574188
Preferred term Zelboraf
R05185426 - Narrower
Concept UI M000623498
Preferred term R05185426



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey