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Descriptor English: HIV Protease
Descriptor Spanish: Proteasa del VIH
Descriptor proteasa del VIH
Entry term(s) proteasa del HTLV-III
proteinasa del VIH
Scope note: Enzima del virus de la inmunodeficiencia humana que se requiere para la segmentación posterior a la traducción de las poliproteínas precursoras gag y gag-pol para formar productos funcionales necesarios para el ensamblaje vírico. La proteasa del VIH es una aspártico-proteasa codificada por el extremo amínico del gen pol.
Descriptor Portuguese: Protease de HIV
Descriptor French: Protéase du VIH
Entry term(s): HIV Proteinase
HIV p16 protease
HTLV III Protease
HTLV-III Protease
Protease, HIV
Protease, HTLV-III
p16 pol gene product, HIV
p16 protease, HIV
Tree number(s): D08.811.277.656.074.500.340
D08.811.277.656.300.048.340
D08.811.277.656.979.500
D12.776.964.775.375.545.750
D12.776.964.900.500.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016333
Scope note: Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:HIV Protease Inhibitors
Registry Number: EC 3.4.23.-
Previous Indexing: Gene Products, pol (1990)
Peptide Peptidohydrolases (1987-1990)
Public MeSH Note: 91
History Note: 91
DeCS ID: 28981
Unique ID: D016333
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/06/07
Revision Date: 2009/07/06
HIV Protease - Preferred
Concept UI M0024965
Scope note Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.
Preferred term HIV Protease
Entry term(s) HIV Proteinase
HIV p16 protease
HTLV III Protease
HTLV-III Protease
Protease, HIV
Protease, HTLV-III
p16 pol gene product, HIV
p16 protease, HIV



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