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Descriptor English: Endothelin-Converting Enzymes
Descriptor Spanish: Enzimas Convertidoras de Endotelina
Descriptor enzimas convertidoras de endotelina
Entry term(s) ECE-1beta
enzima 1 convertidora de endotelina
enzima 1a convertidora de endotelina
enzima 1b convertidora de endotelina
enzima 2 convertidora de endotelina
enzima II convertidora de endotelina
enzima convertidora de endotelina
enzima convertidora de endotelina 1
enzima convertidora de endotelina 1a
enzima convertidora de endotelina 1b
enzima convertidora de endotelina 2
enzima convertidora de endotelina II
enzima convertidora de endotelina-1
enzima convertidora de endotelina-1a
enzima convertidora de endotelina-1b
enzima convertidora de endotelina-2
enzima convertidora de endotelina-II
metaloproteasa 2 convertidora de endotelina
metaloproteasa ECE-2
metaloproteasa convertidora de endotelina 2
metaloproteasa convertidora de endotelina-2
Scope note: Metalopeptidasas que convierten la BIG ENDOTELINA en ENDOTELINA-1.
Descriptor Portuguese: Enzimas Conversoras de Endotelina
Descriptor French: Enzymes de conversion de l'endothéline
Entry term(s): ECE-1beta
ECE-2, Metalloprotease
Endothelin Converting Enzyme
Endothelin Converting Enzyme 1
Endothelin Converting Enzyme 1a
Endothelin Converting Enzyme 1b
Endothelin Converting Enzyme 2
Endothelin Converting Enzyme II
Endothelin Converting Enzyme-1a
Endothelin Converting Enzymes
Endothelin Converting Metalloprotease 2
Endothelin-Converting Enzyme
Endothelin-Converting Enzyme 1
Endothelin-Converting Enzyme 2
Endothelin-Converting Enzyme II
Endothelin-Converting Enzyme-1b
Endothelin-Converting Metalloprotease 2
Metalloprotease ECE 2
Metalloprotease ECE-2
Tree number(s): D08.811.277.656.074.500.270
D08.811.277.656.300.048.270
D08.811.277.656.300.480.229
D08.811.277.656.675.374.229
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072396
Scope note: Metalloendopeptidases which convert BIG ENDOTHELIN to ENDOTHELIN-1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.24.71
Public MeSH Note: 2017; ENDOTHELIN CONVERTING ENZYMES was indexed under METALLOENDOPEPTIDASES and ASPARTIC ACID ENDOPEPTIDASES 1991-2016; and under PEPTIDE PEPTIDOHYDROLASES 1990-1991
History Note: 2017 (1990)
DeCS ID: 56480
Unique ID: D000072396
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/27
Endothelin-Converting Enzymes - Preferred
Concept UI M000617021
Scope note Metalloendopeptidases which convert BIG ENDOTHELIN to ENDOTHELIN-1.
Preferred term Endothelin-Converting Enzymes
Entry term(s) Endothelin Converting Enzyme
Endothelin Converting Enzymes
Endothelin-Converting Enzyme
Endothelin-Converting Enzyme 1 - Narrower
Concept UI M0539212
Scope note Converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond. Mutations in the endothelin-converting enzyme 1 (ECE1) gene are associated with cases of HIRSCHSPRUNG DISEASE with cardiac defects and autonomic dysfunction.
Preferred term Endothelin-Converting Enzyme 1
Entry term(s) Endothelin Converting Enzyme 1
Endothelin-Converting Enzyme-1b - Narrower
Concept UI M0177319
Preferred term Endothelin-Converting Enzyme-1b
Entry term(s) ECE-1beta
Endothelin Converting Enzyme 1b
Endothelin Converting Enzyme-1a - Narrower
Concept UI M0177318
Preferred term Endothelin Converting Enzyme-1a
Entry term(s) Endothelin Converting Enzyme 1a
Endothelin-Converting Enzyme 2 - Narrower
Concept UI M0482654
Scope note An integral membrane metalloendodpeptidase which converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond . It is also involved in the processing of various neuroendocrine peptides and may have methyltransferase activity.
Preferred term Endothelin-Converting Enzyme 2
Entry term(s) ECE-2, Metalloprotease
Endothelin Converting Enzyme 2
Endothelin Converting Enzyme II
Endothelin Converting Metalloprotease 2
Endothelin-Converting Enzyme II
Endothelin-Converting Metalloprotease 2
Metalloprotease ECE 2
Metalloprotease ECE-2



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