Descriptor English: | Endothelin-Converting Enzymes | ||||||
Descriptor Spanish: |
Enzimas Convertidoras de Endotelina
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Descriptor Portuguese: | Enzimas Conversoras de Endotelina | ||||||
Descriptor French: | Enzymes de conversion de l'endothéline | ||||||
Entry term(s): |
ECE-1beta ECE-2, Metalloprotease Endothelin Converting Enzyme Endothelin Converting Enzyme 1 Endothelin Converting Enzyme 1a Endothelin Converting Enzyme 1b Endothelin Converting Enzyme 2 Endothelin Converting Enzyme II Endothelin Converting Enzyme-1a Endothelin Converting Enzymes Endothelin Converting Metalloprotease 2 Endothelin-Converting Enzyme Endothelin-Converting Enzyme 1 Endothelin-Converting Enzyme 2 Endothelin-Converting Enzyme II Endothelin-Converting Enzyme-1b Endothelin-Converting Metalloprotease 2 Metalloprotease ECE 2 Metalloprotease ECE-2 |
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Tree number(s): |
D08.811.277.656.074.500.270 D08.811.277.656.300.048.270 D08.811.277.656.300.480.229 D08.811.277.656.675.374.229 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000072396 | ||||||
Scope note: | Metalloendopeptidases which convert BIG ENDOTHELIN to ENDOTHELIN-1. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 3.4.24.71 | ||||||
Public MeSH Note: | 2017; ENDOTHELIN CONVERTING ENZYMES was indexed under METALLOENDOPEPTIDASES and ASPARTIC ACID ENDOPEPTIDASES 1991-2016; and under PEPTIDE PEPTIDOHYDROLASES 1990-1991 |
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History Note: | 2017 (1990) |
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DeCS ID: | 56480 | ||||||
Unique ID: | D000072396 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2017/01/01 | ||||||
Date of Entry: | 2016/07/08 | ||||||
Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Endothelin-Converting Enzymes
- Preferred
Endothelin-Converting Enzyme 1
- Narrower
Endothelin-Converting Enzyme-1b
- Narrower
Endothelin Converting Enzyme-1a
- Narrower
Endothelin-Converting Enzyme 2
- Narrower
Concept UI |
M000617021 |
Scope note | Metalloendopeptidases which convert BIG ENDOTHELIN to ENDOTHELIN-1. |
Preferred term | Endothelin-Converting Enzymes |
Entry term(s) |
Endothelin Converting Enzyme Endothelin Converting Enzymes Endothelin-Converting Enzyme |
Concept UI |
M0539212 |
Scope note | Converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond. Mutations in the endothelin-converting enzyme 1 (ECE1) gene are associated with cases of HIRSCHSPRUNG DISEASE with cardiac defects and autonomic dysfunction. |
Preferred term | Endothelin-Converting Enzyme 1 |
Entry term(s) |
Endothelin Converting Enzyme 1 |
Concept UI |
M0177319 |
Preferred term | Endothelin-Converting Enzyme-1b |
Entry term(s) |
ECE-1beta Endothelin Converting Enzyme 1b |
Concept UI |
M0177318 |
Preferred term | Endothelin Converting Enzyme-1a |
Entry term(s) |
Endothelin Converting Enzyme 1a |
Concept UI |
M0482654 |
Scope note | An integral membrane metalloendodpeptidase which converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond . It is also involved in the processing of various neuroendocrine peptides and may have methyltransferase activity. |
Preferred term | Endothelin-Converting Enzyme 2 |
Entry term(s) |
ECE-2, Metalloprotease Endothelin Converting Enzyme 2 Endothelin Converting Enzyme II Endothelin Converting Metalloprotease 2 Endothelin-Converting Enzyme II Endothelin-Converting Metalloprotease 2 Metalloprotease ECE 2 Metalloprotease ECE-2 |
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