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Descriptor English: Filipin
Descriptor Spanish: Filipina
Descriptor filipina
Entry term(s) filipina III
Scope note: Complejo de antibióticos poliénicos obtenidos de Streptomyces filipinensis. La filipina III altera la función de la membrana al interferir con los esteroles de la membrana, inhibe la respiración mitocondrial y ha sido propuesto como agente antifúngico. Las filipinas I, II y IV son menos importantes.
Descriptor Portuguese: Filipina
Descriptor French: Filipine
Entry term(s): Filipine I
Filipine II
Filipine III
Filipine IV
NSC-3364
NSC3364
U-5956
U5956
Tree number(s): D02.455.326.271.665.325
D02.540.576.500.996
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005372
Scope note: A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anti-Bacterial Agents
Antifungal Agents
Antiviral Agents
Registry Number: 87Z59R7D14
DeCS ID: 29392
Unique ID: D005372
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2015/06/22
Filipine - Preferred
Concept UI M0008473
Preferred term Filipine
Entry term(s) Filipine III
Filipine II - Related but not broader or narrower
Concept UI M0008475
Preferred term Filipine II
NSC-3364 - Narrower
Concept UI M0351805
Preferred term NSC-3364
Entry term(s) NSC3364
U-5956 - Narrower
Concept UI M0351804
Preferred term U-5956
Entry term(s) U5956
Filipine I - Related but not broader or narrower
Concept UI M0008474
Preferred term Filipine I
Filipine IV - Related but not broader or narrower
Concept UI M0008476
Preferred term Filipine IV



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