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Descriptor English: Interferons
Descriptor Spanish: Interferones
Descriptor interferones
Scope note: Proteínas segregadas por células vertebradas en respuesta a una amplia variedad de inductores. Confieren resistencia frente a a muchos virus diferentes, inhiben la proliferación de células normales y malignas, dificultad la multiplicación de parásitos intracelulares, aumentan la fagocitosis de macrófagos y granulocitos, aumentan la actividad de las células asesinas naturales y muestran otras varias funciones inmunomoduladoras.
Descriptor Portuguese: Interferons
Descriptor French: Interférons
Entry term(s): Interferon
Tree number(s): D12.644.276.374.440
D12.776.467.374.440
D23.529.374.440
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007372
Scope note: Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
Annotation: "stimulators" or "inducers" = INTERFERON INDUCERS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Antineoplastic Agents
Antiviral Agents
Registry Number: 9008-11-1
Public MeSH Note: 83; was INTERFERON 1963-82
Online Note: use INTERFERONS to search INTERFERON 1966-82
History Note: 83; was INTERFERON 1963-82
Related: Receptors, Interferon MeSH
DeCS ID: 29469
Unique ID: D007372
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/22
Interferons - Preferred
Concept UI M0011491
Scope note Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
Preferred term Interferons
Entry term(s) Interferon



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