Descriptor English: | Swainsonine | ||||
Descriptor Spanish: |
Swainsonina
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Descriptor Portuguese: | Swainsonina | ||||
Descriptor French: | Tridolgosir | ||||
Entry term(s): |
Swainsonine, (1R-(2 beta,8a alpha))-Isomer Swainsonine, (2 beta,8a alpha)-Isomer Swainsonine, (8 alpha)-Isomer Swainsonine, (8 alpha,8a alpha)-Isomer Swainsonine, (8a alpha)-Isomer |
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Tree number(s): |
D03.132.830 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017026 | ||||
Scope note: | An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Adjuvants, Immunologic Antineoplastic Agents, Phytogenic Enzyme Inhibitors |
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Registry Number: | RSY4RK37KQ | ||||
CAS Type 1 Name: | 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))- | ||||
Previous Indexing: |
Alkaloids (1980-1991) |
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Public MeSH Note: | 92; SWAINSONINE was indexed under ALKALOIDS 1981-91 |
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Online Note: | use SWAINSONINE (NM) to search SWAINSONINE 1981-91 |
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History Note: | 92; was SWAINSONINE (NM) 1981-91 |
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DeCS ID: | 29798 | ||||
Unique ID: | D017026 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1992/01/01 | ||||
Date of Entry: | 1991/07/12 | ||||
Revision Date: | 2013/07/08 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Swainsonine
- Preferred
Swainsonine, (8a alpha)-Isomer
- Narrower
Swainsonine, (8 alpha)-Isomer
- Narrower
Swainsonine, (8 alpha,8a alpha)-Isomer
- Narrower
Swainsonine, (1R-(2 beta,8a alpha))-Isomer
- Narrower
Swainsonine, (2 beta,8a alpha)-Isomer
- Narrower
Concept UI |
M0025867 |
Scope note | An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity. |
Preferred term | Swainsonine |
Concept UI |
M0329437 |
Preferred term | Swainsonine, (8a alpha)-Isomer |
Concept UI |
M0329321 |
Preferred term | Swainsonine, (8 alpha)-Isomer |
Concept UI |
M0329320 |
Preferred term | Swainsonine, (8 alpha,8a alpha)-Isomer |
Concept UI |
M0329436 |
Preferred term | Swainsonine, (1R-(2 beta,8a alpha))-Isomer |
Concept UI |
M0329380 |
Preferred term | Swainsonine, (2 beta,8a alpha)-Isomer |
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