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Descriptor English: Lobeline
Descriptor Spanish: Lobelina
Descriptor lobelina
Scope note: Alcaloide que tienen acciones similares a la NICOTINA sobre los receptores nicotínicos colinérgicos pero es menos potente. Ha sido propuesto para una variedad de usos terapéuticos, como enfermedades respiratorias, enfermedades vasculares periféricas, insomnio y para dejar de fumar.
Descriptor Portuguese: Lobelina
Descriptor French: Lobéline
Entry term(s): Lobeline Sulfate
Smokeless
Sulfate, Lobeline
Tree number(s): D03.132.478
D03.383.621.418
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008120
Scope note: An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
Annotation: /biosyn permitted if by plant
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Ganglionic Stimulants
Nicotinic Agonists
Respiratory System Agents
Registry Number: D0P25S3P81
CAS Type 1 Name: Ethanone, 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl)-1-phenyl-, (2R-(2alpha,6alpha(S*)))-
DeCS ID: 8297
Unique ID: D008120
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Lobeline - Preferred
Concept UI M0012663
Scope note An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
Preferred term Lobeline
Smokeless - Narrower
Concept UI M0463947
Preferred term Smokeless
Lobeline Sulfate - Narrower
Concept UI M0463946
Preferred term Lobeline Sulfate
Entry term(s) Sulfate, Lobeline



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