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Descriptor English: Colchicine
Descriptor Spanish: Colchicina
Descriptor colchicina
Scope note: Principal alcaloide de la Colchicum autumnale L. que también se encuentra en otras especies Colchicum. Su uso terapéutico más importante es en el tratamiento de la gota, aunque también se ha utilizado para tratar la fiebre mediterránea familiar (ENFERMEDAD PERIÓDICA).
Descriptor Portuguese: Colchicina
Descriptor French: Colchicine
Entry term(s): Colchicine, (+-)-Isomer
Colchicine, (R)-Isomer
Tree number(s): D03.132.225
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003078
Scope note: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Gout Suppressants
Tubulin Modulators
Registry Number: SML2Y3J35T
CAS Type 1 Name: Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-
DeCS ID: 27974
Unique ID: D003078
NLM Classification: QV 98
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Colchicine - Preferred
Concept UI M0004732
Scope note A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).
Preferred term Colchicine
Colchicine, (R)-Isomer - Narrower
Concept UI M0330575
Preferred term Colchicine, (R)-Isomer
Colchicine, (+-)-Isomer - Narrower
Concept UI M0330574
Preferred term Colchicine, (+-)-Isomer



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