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Descriptor in English: Chaperonins
Descriptor in Spanish: Chaperoninas
Descriptor in Portuguese: Chaperoninas
Descriptor in French: Chaperonines
Entry term(s): Chaperonin Complexes
Chaperonin Family
Chaperonin Protein Complex
Tree number(s): D08.811.277.040.025.142
D12.776.580.216.210
Scope note: A family of multisubunit protein complexes that form into large cylindrical structures which bind to and encapsulate non-native proteins. Chaperonins utilize the energy of ATP hydrolysis to enhance the efficiency of PROTEIN FOLDING reactions and thereby help proteins reach their functional conformation. The family of chaperonins is split into GROUP I CHAPERONINS, and GROUP II CHAPERONINS, with each group having its own repertoire of protein subunits and subcellular preferences.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Online Note: use CHAPERONINS (NM) to search CHAPERONIN FAMILY 1989-94
History Note: 95; was CHAPERONIN FAMILY (NM) 1989-94
DeCS UI: 32312
Descriptor UI: D018833
Date Established: 1995/01/01
Date of Entry: 1994/05/31
Revision Date: 2009/07/06
Chaperonins - Preferred
Concept UI M0028187
Scope note A family of multisubunit protein complexes that form into large cylindrical structures which bind to and encapsulate non-native proteins. Chaperonins utilize the energy of ATP hydrolysis to enhance the efficiency of PROTEIN FOLDING reactions and thereby help proteins reach their functional conformation. The family of chaperonins is split into GROUP I CHAPERONINS, and GROUP II CHAPERONINS, with each group having its own repertoire of protein subunits and subcellular preferences.
Preferred term Chaperonins
Entry term(s) Chaperonin Family
Chaperonin Complexes - Narrower
Concept UI M0527154
Preferred term Chaperonin Complexes
Entry term(s) Chaperonin Protein Complex



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