| Descriptor English: | MutS Proteins | ||||||
| Descriptor Spanish: |
Proteínas MutS
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| Descriptor Portuguese: | Proteínas MutS | ||||||
| Descriptor French: | Protéines MutS | ||||||
| Entry term(s): |
Homolog Protein, MutS Homolog Proteins, MutS Homolog, MutS MutS Homolog MutS Homolog Protein MutS Homolog Proteins MutS Homologs MutS Protein Protein, MutS Protein, MutS Homolog Proteins, MutS Homolog |
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| Tree number(s): |
D08.811.074.844 D08.811.277.040.025.292 D12.776.260.556 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074080 | ||||||
| Scope note: | DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.6.1.3 | ||||||
| Previous Indexing: |
Adenosine Triphosphatases (1997-2017) DNA-Binding Proteins (1997-2017) MutS DNA Mismatch-Binding Protein (2006-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 56991 | ||||||
| Unique ID: | D000074080 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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MutS Proteins
- Preferred
MutS Homolog Proteins
- Narrower
| Concept UI |
M000625423 |
| Scope note | DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity. |
| Preferred term | MutS Proteins |
| Entry term(s) |
MutS Protein Protein, MutS |
| Concept UI |
M000625424 |
| Preferred term | MutS Homolog Proteins |
| Entry term(s) |
Homolog Protein, MutS Homolog Proteins, MutS Homolog, MutS MutS Homolog MutS Homolog Protein MutS Homologs Protein, MutS Homolog Proteins, MutS Homolog |
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