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Descriptor English: Antibody-Dependent Enhancement
Descriptor Spanish: Acrecentamiento Dependiente de Anticuerpo
Descriptor facilitación dependiente de anticuerpos
Scope note: Aumento de la infectividad viral causada por anticuerpos no neutralizantes. Existen al menos dos mecanismos conocidos para explicarlo: por mediación de receptores Fc (RECEPTORES FC) o de receptores del complemento (RECEPTORES DEL COMPLEMENTO). El virus forma un complejo con la IgG antiviral y se une a receptores Fc, o es recubierto por la IgM antiviral y se une a los receptores del complemento.
Descriptor Portuguese: Anticorpos Facilitadores
Descriptor French: Facilitation dépendante des anticorps
Entry term(s): Antibody Dependent Enhancement
Antibody-Dependent Enhancements
Enhancement, Antibody-Dependent
Tree number(s): G06.920.095
G12.113
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019067
Scope note: Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by Fc receptors (RECEPTORS, FC) or by complement receptors (RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral IMMUNOGLOBULIN G and binds to Fc receptors, or virus is coated with antiviral IMMUNOGLOBULIN M and binds to complement receptors.
Annotation: enhancement of viral infectivity: read MeSH definition
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 96
History Note: 96
DeCS ID: 32854
Unique ID: D019067
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2016/02/09
Antibody-Dependent Enhancement - Preferred
Concept UI M0028464
Scope note Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by Fc receptors (RECEPTORS, FC) or by complement receptors (RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral IMMUNOGLOBULIN G and binds to Fc receptors, or virus is coated with antiviral IMMUNOGLOBULIN M and binds to complement receptors.
Preferred term Antibody-Dependent Enhancement
Entry term(s) Antibody Dependent Enhancement
Antibody-Dependent Enhancements
Enhancement, Antibody-Dependent



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