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Descriptor English: Coproporphyrinogen Oxidase
Descriptor Spanish: Coproporfirinógeno Oxidasa
Descriptor coproporfirinógeno oxidasa
Entry term(s) coproporfirinogenasa
Scope note: Enzima que cataliza la descarboxilación oxidativa del coproporfirinógeno III a protoporfirinógeno IX mediante la conversión de dos grupos propionato en dos grupos vinilo. Es la sexta enzima en la vía de 8 enzimas de la biosíntesis del HEMO y es codificada por el gen CPO. Las mutaciones del gen CPO dan lugar a COPROPORFIRIA HEREDITARIA.
Descriptor Portuguese: Coproporfirinogênio Oxidase
Descriptor French: Coproporphyrinogen oxidase
Entry term(s): Coproporphyrinogen III Oxidases
Coproporphyrinogenase
III Oxidases, Coproporphyrinogen
Oxidase, Coproporphyrinogen
Oxidases, Coproporphyrinogen III
Tree number(s): D08.811.682.660.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003304
Scope note: An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Coproporphyria, Hereditary
Registry Number: EC 1.3.3.3
CAS Type 1 Name: Coproporphyrinogen:oxygen oxidoreductase (decarboxylating)
Previous Indexing: Carboxy-Lyases (1972-1974)
Coproporphyrins (1975)
Oxidoreductases (1975)
Porphyrins (1972-1974)
Public MeSH Note: 91; was see under OXIDOREDUCTASES 1976-90
History Note: 91(76); was see under OXIDOREDUCTASES 1976-90
DeCS ID: 3324
Unique ID: D003304
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/25
Revision Date: 2008/07/08
Coproporphyrinogen Oxidase - Preferred
Concept UI M0005157
Scope note An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.
Preferred term Coproporphyrinogen Oxidase
Entry term(s) Coproporphyrinogen III Oxidases
Coproporphyrinogenase
III Oxidases, Coproporphyrinogen
Oxidase, Coproporphyrinogen
Oxidases, Coproporphyrinogen III



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