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Descriptor English: Dihydrouracil Dehydrogenase (NAD+)
Descriptor Spanish: Dihidrouracilo-Deshidrogenasa (NAD+)
Descriptor dihidrouracilo deshidrogenasa (NAD+)
Scope note: Enzima que cataliza la oxidación del 5,6-dihidrouracilo a URACILO usando NAD como cofactor. Esta enzima también interviene en el catabolismo del antimetabolito 5-FLUOROURACILO.
Descriptor Portuguese: Di-Hidrouracila Desidrogenase (NAD+)
Descriptor French: Dihydrouracil dehydrogenase (NAD+)
Entry term(s): Dehydrogenase, Dihydrouracil
Dihydrothymine Dehydrogenase (NAD)
Dihydrouracil Dehydrogenase
Dihydrouracil Dehydrogenase (NAD)
Tree number(s): D08.811.682.660.325
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050744
Scope note: An enzyme that catalyzes the oxidation of 5,6-dihydrouracil to URACIL using NAD as a cofactor. This enzyme also plays a role in the catabolism of the antimetabolite 5-FLUOROURACIL.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.3.1.1
Previous Indexing: Oxidoreductases (1983-2003)
Oxidoreductases Acting on CH-CH Group Donors (2004-2005)
Public MeSH Note: 2006; DIHYDROURACIL DEHYDROGENASE (NAD+) was indexed under OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS 2004-2005, OXIDOREDUCTASES 1983-2003, & URACIL 1970-1982
History Note: 2006(1970)
DeCS ID: 50624
Unique ID: D050744
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2005/07/11
Dihydrouracil Dehydrogenase (NAD+) - Preferred
Concept UI M0073260
Scope note An enzyme that catalyzes the oxidation of 5,6-dihydrouracil to URACIL using NAD as a cofactor. This enzyme also plays a role in the catabolism of the antimetabolite 5-FLUOROURACIL.
Preferred term Dihydrouracil Dehydrogenase (NAD+)
Entry term(s) Dehydrogenase, Dihydrouracil
Dihydrothymine Dehydrogenase (NAD)
Dihydrouracil Dehydrogenase
Dihydrouracil Dehydrogenase (NAD)



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