| Descriptor English: | Dihydrouracil Dehydrogenase (NADP) | ||||||
| Descriptor Spanish: |
Dihidrouracilo Deshidrogenasa (NADP)
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| Descriptor Portuguese: | Di-Hidrouracila Desidrogenase (NADP) | ||||||
| Descriptor French: | Dihydrouracil dehydrogenase (NADP) | ||||||
| Entry term(s): |
Dehydrogenase, Dihydropyrimidine Dihydropyrimidine Dehydrogenase Dihydrothymine Dehydrogenase (NADP) |
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| Tree number(s): |
D08.811.682.660.350 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D042943 | ||||||
| Scope note: | An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
deficiency:Dihydropyrimidine Dehydrogenase Deficiency
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| Registry Number: | EC 1.3.1.2 | ||||||
| Previous Indexing: |
Oxidoreductases (1980-2003) Uracil (1979) |
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| Public MeSH Note: | 2004; DIHYDROURACIL DEHYDROGENASE (NADP) was indexed under OXIDOREDUCTASES 1983-2003; & under URACIL 1979 |
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| History Note: | 2004; use DIHYDROURACIL DEHYDROGENASE (NADP) (NM) 1980-2003 |
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| DeCS ID: | 38220 | ||||||
| Unique ID: | D042943 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2013/07/08 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Dihydrouracil Dehydrogenase (NADP)
- Preferred
| Concept UI |
M0073263 |
| Scope note | An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL. |
| Preferred term | Dihydrouracil Dehydrogenase (NADP) |
| Entry term(s) |
Dehydrogenase, Dihydropyrimidine Dihydropyrimidine Dehydrogenase Dihydrothymine Dehydrogenase (NADP) |
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