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Descriptor English: 15-Oxoprostaglandin 13-Reductase
Descriptor Spanish: 15-Oxoprostaglandina 13-Reductasa
Descriptor 15-oxoprostaglandina 13-reductasa
Entry term(s) prostaglandina delta-13-reductasa
prostaglandina-13,14-reductasa
Scope note: (5Z)-(15S)-11 alfa-hydroxy-9,15-dioxoprostanoato:NAD(P)+ delta(13)-oxidoreductasa. Enzima activa en el catabolismo de las prostaglandinas E y F. Cataliza la reducción del doble enlace en la posición 13-14 de las 15-cetoprostaglandinas y utiliza NADPH como cofactor. EC 1.3.1.48.
Descriptor Portuguese: 15-Oxoprostaglandina 13-Redutase
Descriptor French: Prostaglandine reductase
Entry term(s): 13-15-Ketoprostaglandin Reductase, delta
13-Reductase, 15-Ketoprostaglandin delta
13-Reductase, 15-Oxoprostaglandin
15 Ketoprostaglandin delta 13 Reductase
15 Oxoprostaglandin 13 Reductase
15-Ketoprostaglandin delta 13-Reductase
Prostaglandin 13,14 Reductase
Prostaglandin delta 13 Reductase
Prostaglandin delta-13-Reductase
Prostaglandin-13,14-Reductase
Reductase, delta 13-15-Ketoprostaglandin
delta 13 15 Ketoprostaglandin Reductase
delta 13 PG Reductase
delta 13-15-Ketoprostaglandin Reductase
delta 13-Reductase, 15-Ketoprostaglandin
delta-13-PG-Reductase
delta-13-Reductase, Prostaglandin
Tree number(s): D08.811.682.660.490
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011452
Scope note: (5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. EC 1.3.1.48.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.3.1.48
Previous Indexing: Oxidoreductases (1966-1977)
Prostaglandins (1966-1977)
specific prostaglandin (1975-1977)
Public MeSH Note: 94; was PROSTAGLANDIN-13,14-REDUCTASE 1978-93 (see under OXIDOREDUCTASES 1978-90); DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE was indexed under PROSTAGLANDIN-13,14-REDUCTASE 1981-93 and OXIDOREDUCTASES & PROSTAGLANDINS 1976-80; PROSTAGLANDIN DELTA 13 REDUCTASE was indexed under OXIDOREDUCTASES 1981-93
Online Note: use 15-OXOPROSTAGLANDIN 13-REDUCTASE to search PROSTAGLANDIN-13,14-REDUCTASE 1978-93; use 15-OXOPROSTAGLANDIN 13-REDUCTASE (NM) to search DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE 1980-93 & PROSTAGLANDIN DELTA 13 REDUCTASE 1981-93
History Note: 94; was PROSTAGLANDIN-13,14-REDUCTASE 1978-93 (see under OXIDOREDUCTASES 1978-90); DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE was (NM) 1976-93; PROSTAGLANDIN DELTA 13 REDUCTASE was (NM) 1981-93
Entry Version: OXOPG REDUCTASE
DeCS ID: 31899
Unique ID: D011452
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/05/23
Revision Date: 2005/06/30
15-Oxoprostaglandin 13-Reductase - Preferred
Concept UI M0017804
Scope note (5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. EC 1.3.1.48.
Preferred term 15-Oxoprostaglandin 13-Reductase
Entry term(s) 13-15-Ketoprostaglandin Reductase, delta
13-Reductase, 15-Ketoprostaglandin delta
13-Reductase, 15-Oxoprostaglandin
15 Ketoprostaglandin delta 13 Reductase
15 Oxoprostaglandin 13 Reductase
15-Ketoprostaglandin delta 13-Reductase
Prostaglandin 13,14 Reductase
Prostaglandin delta 13 Reductase
Prostaglandin delta-13-Reductase
Prostaglandin-13,14-Reductase
Reductase, delta 13-15-Ketoprostaglandin
delta 13 15 Ketoprostaglandin Reductase
delta 13 PG Reductase
delta 13-15-Ketoprostaglandin Reductase
delta 13-Reductase, 15-Ketoprostaglandin
delta-13-PG-Reductase
delta-13-Reductase, Prostaglandin



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