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Descriptor English: Dihydroorotate Oxidase
Descriptor Spanish: Dihidroorotato Oxidasa
Descriptor dihidroorotato oxidasa
Scope note: Enzima que, en el transcurso de la biosíntesis de pirimidina, cataliza la oxidación del ácido dihidroorótico a ácido orótico, utilizando oxígeno como aceptor de electrones. Esta enzima es una flavoproteína que contiene FLAVINA-ADENINA DINUCLEÓTIDO y MONONUCLEÓTIDO DE FLAVINA como centros de hierro-azufre.
Descriptor Portuguese: Di-Hidrorotato Oxidase
Descriptor French: Dihydroorotate oxidase
Entry term(s): Dihydro Orotate Oxidase
Dihydro-Orotate Oxidase
Oxidase, Dihydro-Orotate
Oxidase, Dihydroorotate
Tree number(s): D08.811.682.660.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004081
Scope note: An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.3.98.1
CAS Type 1 Name: (S)-Dihydroorotate:oxygen oxidoreductase
Previous Indexing: Orotic Acid (1966-1976)
Oxidoreductases (1966-1976)
Public MeSH Note: 94; was DIHYDRO-OROTATE OXIDASE 1977-93 (see under OXIDOREDUCTASES 1977-90); DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE were see DIHYDRO-OROTATE OXIDASE 1977-93
Online Note: use DIHYDROOROTATE OXIDASE to search DIHYDRO-OROTATE OXIDASE, DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE 1977-93
History Note: 94; was DIHYDRO-OROTATE OXIDASE 1977-93 (see under OXIDOREDUCTASES 1977-90); DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE were see DIHYDRO-OROTATE OXIDASE 1977-93
DeCS ID: 31730
Unique ID: D004081
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/27
Revision Date: 2012/07/03
Dihydroorotate Oxidase - Preferred
Concept UI M0006392
Scope note An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1.
Preferred term Dihydroorotate Oxidase
Entry term(s) Dihydro Orotate Oxidase
Dihydro-Orotate Oxidase
Oxidase, Dihydro-Orotate
Oxidase, Dihydroorotate



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