Descriptor English: | Protoporphyrinogen Oxidase | ||||
Descriptor Spanish: |
Protoporfirinógeno-Oxidasa
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Descriptor Portuguese: | Protoporfirinogênio Oxidase | ||||
Descriptor French: | Protoporphyrinogen oxidase | ||||
Entry term(s): |
Dehydrogenase, Protoporphyrinogen Oxidase, Protoporphyrinogen Oxidase, Protoporphyrinogen IX Protoporphyrinogen Dehydrogenase Protoporphyrinogen IX Oxidase Protoporphyrinogenase Protox |
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Tree number(s): |
D08.811.682.660.600 D12.776.543.697 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050768 | ||||
Scope note: | A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Entry Combination: |
deficiency:Porphyria, Variegate
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Registry Number: | EC 1.3.3.4 | ||||
Previous Indexing: |
Oxidoreductases (1993-2003) Oxidoreductases Acting on CH-CH Group Donors (2004-2005) Porphyrins (1975-1976) Protoporphyrins (1975-1982) |
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Public MeSH Note: | 2006; PROTOPORPHYRINOGEN OXIDASE was indexed under OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS 2004-2005, under OXIDOREDUCTASES 1993-2003, under PORPHYRINS 1975-1976, and under PROTOPORPHYRINS 1975-1982 |
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History Note: | 2006(1975) |
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DeCS ID: | 50629 | ||||
Unique ID: | D050768 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 2006/01/01 | ||||
Date of Entry: | 2005/06/30 | ||||
Revision Date: | 2009/07/15 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Protoporphyrinogen Oxidase
- Preferred
Concept UI |
M0078571 |
Scope note | A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase. |
Preferred term | Protoporphyrinogen Oxidase |
Entry term(s) |
Dehydrogenase, Protoporphyrinogen Oxidase, Protoporphyrinogen Oxidase, Protoporphyrinogen IX Protoporphyrinogen Dehydrogenase Protoporphyrinogen IX Oxidase Protoporphyrinogenase Protox |
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