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Descriptor in English: Guanidine
Descriptor in Spanish: Guanidina
Descriptor in Portuguese: Guanidina
Descriptor in French: Guanidine
Entry term(s): Chloride, Guanidinium
Chloride, Guanidium
Guanidine Hydrochloride
Guanidine Monohydrate
Guanidine Monohydrobromide
Guanidine Monohydrochloride
Guanidine Monohydroiodine
Guanidine Nitrate
Guanidine Phosphate
Guanidine Sulfate
Guanidine Sulfate (1:1)
Guanidine Sulfate (2:1)
Guanidine Sulfite (1:1)
Guanidinium
Guanidinium Chloride
Guanidium Chloride
Hydrochloride, Guanidine
Monohydrate, Guanidine
Monohydrobromide, Guanidine
Monohydrochloride, Guanidine
Monohydroiodine, Guanidine
Nitrate, Guanidine
Phosphate, Guanidine
Sulfate, Guanidine
Tree number(s): D02.078.370.472
Scope note: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 98; use GUANIDINE (NM) 1974-97
DeCS UI: 33385
Descriptor UI: D019791
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2013/07/08
Guanidine - Preferred
Concept UI M0029365
Scope note A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Preferred term Guanidine
Entry term(s) Guanidinium
Guanidine Monohydrate - Narrower
Concept UI M0329110
Preferred term Guanidine Monohydrate
Entry term(s) Monohydrate, Guanidine
Guanidine Monohydrobromide - Narrower
Concept UI M0329106
Preferred term Guanidine Monohydrobromide
Entry term(s) Monohydrobromide, Guanidine
Guanidine Monohydroiodine - Narrower
Concept UI M0329105
Preferred term Guanidine Monohydroiodine
Entry term(s) Monohydroiodine, Guanidine
Guanidine Sulfite (1:1) - Narrower
Concept UI M0329112
Preferred term Guanidine Sulfite (1:1)
Guanidine Phosphate - Narrower
Concept UI M0329104
Preferred term Guanidine Phosphate
Entry term(s) Phosphate, Guanidine
Guanidine Sulfate - Narrower
Concept UI M0329103
Preferred term Guanidine Sulfate
Entry term(s) Sulfate, Guanidine
Guanidine Sulfate (1:1) - Narrower
Concept UI M0329111
Preferred term Guanidine Sulfate (1:1)
Guanidine Sulfate (2:1) - Narrower
Concept UI M0329109
Preferred term Guanidine Sulfate (2:1)
Guanidine Hydrochloride - Narrower
Concept UI M0329107
Preferred term Guanidine Hydrochloride
Entry term(s) Chloride, Guanidinium
Chloride, Guanidium
Guanidine Monohydrochloride
Guanidinium Chloride
Guanidium Chloride
Hydrochloride, Guanidine
Monohydrochloride, Guanidine
Guanidine Nitrate - Narrower
Concept UI M0329108
Preferred term Guanidine Nitrate
Entry term(s) Nitrate, Guanidine



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