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Descriptor in English: Cytarabine
Descriptor in Spanish: Citarabina
Descriptor in Portuguese: Citarabina
Descriptor in French: Cytarabine
Entry term(s): Ara C
Ara-C
Arabinofuranosylcytosine
Arabinoside, Cytosine
Arabinosylcytosine
Aracytidine
Aracytine
Cytarabine Hydrochloride
Cytonal
Cytosar
Cytosar U
Cytosar-U
Cytosine Arabinoside
beta Ara C
beta-Ara C
Tree number(s): D03.383.742.680.245.453
D13.570.065.300
D13.570.685.245.453
Scope note: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 1966
See also the descriptors: Decitabine MeSH
DeCS UI: 3578
Descriptor UI: D003561
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/02/28
Cytarabine - Preferred
Concept UI M0005564
Scope note A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Preferred term Cytarabine
Entry term(s) Arabinofuranosylcytosine
Arabinoside, Cytosine
Arabinosylcytosine
Aracytidine
Cytosine Arabinoside
beta-Ara C - Narrower
Concept UI M0369308
Preferred term beta-Ara C
Entry term(s) beta Ara C
Cytarabine Hydrochloride - Narrower
Concept UI M0005565
Preferred term Cytarabine Hydrochloride
Cytosar - Narrower
Concept UI M0005566
Preferred term Cytosar
Entry term(s) Cytosar U
Cytosar-U
Ara-C - Narrower
Concept UI M0369310
Preferred term Ara-C
Entry term(s) Ara C
Aracytine - Narrower
Concept UI M0369309
Preferred term Aracytine
Cytonal - Narrower
Concept UI M0372750
Preferred term Cytonal



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