Descriptor English: | DNA-Directed DNA Polymerase | ||||||
Descriptor Spanish: |
ADN Polimerasa Dirigida por ADN
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Descriptor Portuguese: | DNA Polimerase Dirigida por DNA | ||||||
Descriptor French: | DNA-directed DNA polymerase | ||||||
Entry term(s): |
DNA Dependent DNA Polymerases DNA Directed DNA Polymerase DNA Polymerase DNA Polymerase N3 DNA Polymerase, DNA-Directed DNA Polymerases DNA Polymerases, DNA-Dependent DNA-Dependent DNA Polymerases Polymerase N3, DNA Polymerase, DNA Polymerase, DNA-Directed DNA Polymerases, DNA Polymerases, DNA-Dependent DNA |
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Tree number(s): |
D08.811.913.696.445.308.300 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D004259 | ||||||
Scope note: | DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. |
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Annotation: | general; prefer specifics |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Entry Combination: |
antagonists & inhibitors:Nucleic Acid Synthesis Inhibitors
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Registry Number: | EC 2.7.7.7 | ||||||
CAS Type 1 Name: | Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) | ||||||
Previous Indexing: |
DNA Nucleotidyltransferases (1968-1976) |
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Public MeSH Note: | 98; see DNA POLYMERASES 1977-97, for DNA POLYMERASE see DNA NUCLEOTIDYLTRANSFERASES 1973-76, see DNA NUCLEOTIDYLTRANSFERASE 1968-72 |
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History Note: | 98(68); for DNA POLYMERASE use DNA NUCLEOTIDYLTRANSFERASES 1968-76 |
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DeCS ID: | 4326 | ||||||
Unique ID: | D004259 | ||||||
NLM Classification: | QU 141 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1977/01/01 | ||||||
Date of Entry: | 1976/04/19 | ||||||
Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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DNA-Directed DNA Polymerase
- Preferred
DNA Polymerase N3
- Narrower
Concept UI |
M0006665 |
Scope note | DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. |
Preferred term | DNA-Directed DNA Polymerase |
Entry term(s) |
DNA Dependent DNA Polymerases DNA Directed DNA Polymerase DNA Polymerase DNA Polymerase, DNA-Directed DNA Polymerases DNA Polymerases, DNA-Dependent DNA-Dependent DNA Polymerases Polymerase, DNA Polymerase, DNA-Directed DNA Polymerases, DNA Polymerases, DNA-Dependent DNA |
Concept UI |
M0006664 |
Preferred term | DNA Polymerase N3 |
Entry term(s) |
Polymerase N3, DNA |
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