| Descriptor English: | DNA Polymerase gamma | ||||||
| Descriptor Spanish: |
ADN Polimerasa gamma
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| Descriptor Portuguese: | DNA Polimerase gama | ||||||
| Descriptor French: | DNA Polymerase gamma | ||||||
| Entry term(s): |
DNA Polymerase Subunit gamma 1 DNA Polymerase Subunit gamma-1 DNA Polymerase, Mitochondrial Mitochondrial DNA Polymerase PolG alpha PolG-alpha Polymerase gamma, DNA Polymerase, Mitochondrial DNA |
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| Tree number(s): |
D08.811.913.696.445.308.300.169 D12.776.575.280 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074002 | ||||||
| Scope note: | A DNA-directed DNA polymerase that functions in the replication of MITOCHONDRIAL DNA. Mutations in the gene that encodes this enzyme (POLG) are associated with some forms of OPHTHALMOPLEGIA, CHRONIC EXTERNAL PROGRESSIVE. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.7.7 | ||||||
| Public MeSH Note: | 2018; DNA POLYMERASE GAMMA was indexed under DNA-DIRECTED DNA POLYMERASE 1997-2017 |
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| History Note: | 2018 (1997) |
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| DeCS ID: | 57031 | ||||||
| Unique ID: | D000074002 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2020/06/22 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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DNA Polymerase gamma
- Preferred
| Concept UI |
M000625126 |
| Scope note | A DNA-directed DNA polymerase that functions in the replication of MITOCHONDRIAL DNA. Mutations in the gene that encodes this enzyme (POLG) are associated with some forms of OPHTHALMOPLEGIA, CHRONIC EXTERNAL PROGRESSIVE. |
| Preferred term | DNA Polymerase gamma |
| Entry term(s) |
DNA Polymerase Subunit gamma 1 DNA Polymerase Subunit gamma-1 DNA Polymerase, Mitochondrial Mitochondrial DNA Polymerase PolG alpha PolG-alpha Polymerase gamma, DNA Polymerase, Mitochondrial DNA |
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