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Descriptor English: DNA Polymerase theta
Descriptor Spanish: ADN Polimerasa theta
Descriptor ADN-polimerasa teta
Entry term(s) ADN-polimerasa POLQ
Scope note: ADN-polimerasa especializada que en los seres humanos está codificada por el gen POLQ. Interviene en las vías de reparación del ADN, como la REPARACIÓN DEL ADN POR UNIÓN DE EXTREMOS y la REPARACIÓN DEL ADN POR RECOMBINACIÓN.
Descriptor Portuguese: DNA Polimerase teta
Descriptor French: Without translation
Entry term(s): DNA Polymerase POLQ
POLQ, DNA Polymerase
Polymerase POLQ, DNA
Polymerase theta, DNA
theta, DNA Polymerase
Tree number(s): D08.811.913.696.445.308.300.622
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097462
Scope note: A specialized DNA polymerase that in humans is encoded by the POLQ gene. It is involved in DNA repair pathways, including DNA END-JOINING REPAIR and RECOMBINATIONAL DNA REPAIR.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.7.-
Public MeSH Note: 2024; DNA POLYMERASE THETA was indexed under DNA-DIRECTED DNA POLYMERASE 1999-2023
History Note: 2024 (1999)
DeCS ID: 60583
Unique ID: D000097462
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/30
DNA Polymerase theta - Preferred
Concept UI M0331871
Scope note A specialized DNA polymerase that in humans is encoded by the POLQ gene. It is involved in DNA repair pathways, including DNA END-JOINING REPAIR and RECOMBINATIONAL DNA REPAIR.
Preferred term DNA Polymerase theta
Entry term(s) DNA Polymerase POLQ
POLQ, DNA Polymerase
Polymerase POLQ, DNA
Polymerase theta, DNA
theta, DNA Polymerase



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